Are DNA fragments in mRNA vaccines dangerous, and can they cause cancer?!
Take a look at the viral claim, and find out what the facts really are!
Claim : DNA Fragments In mRNA Vaccines Can Cause Cancer!
People are sharing video clips and articles about Florida Surgeon General Joseph Ladapo calling for a halt to mRNA vaccines as they can possibly cause cancer.
Recommended : Are Residual DNA In mRNA Vaccines Dangerous?!
No Evidence DNA Fragments In mRNA Vaccines Cause Cancer!
Let’s take a closer look at these claims about DNA fragments in mRNA vaccines causing cancer, and find out what the facts really are!
Fact #1 : Claims Were Made By Joseph Ladapo
First, I should point out that these videos and articles are based on a 3 January 2024 bulletin sent by the Florida Department of Health, in which its Surgeon General Joseph A. Ladapo called for a halt in the use of mRNA COVID-19 vaccines over concerns that they could cause cancer.
Fact #2 : SV40 Promoter Does Not Cause Cancer
Many people are attempting to link the SV40 promoter to the Simian Virus 40, which was suspected to potentially cause cancer in humans after it was found to have contaminated some polio vaccines manufactured from 1955 to 1963.
Decades later, there is still no conclusive evidence that the SV40 virus can cause cancers in humans. However, out of an abundance of caution, the SV40 virus is considered to potentially cause cancer in humans.
Even so, the SV40 promoter is just a DNA fragment from the SV40 virus, that is now used as a genetic tool. It is similar to how botulinum toxin is a treatment derived from the bacteria, Clostridium botulinum. The SV40 promoter itself cannot cause cancer, because it does not include the SV40 virus portion that can potentially cause cancer – the T-antigen.
Recommended : Are mRNA Vaccines Contaminated With SV40 DNA?!
Fact #3 : DNA Fragments Not Limited To mRNA Vaccines
So many articles have been written about the residual DNA fragments in mRNA vaccines that one may think that it’s exclusive to the mRNA vaccine technology. That’s not true.
Residual DNA fragments are found in all vaccines and biological products manufactured in any kind of biological cell. The risk of residual DNA has also been investigated for about 60 years now.
To be clear – residual DNA isn’t new or exclusive to mRNA vaccine technology. It is a byproduct of using biological cells to produce biological products.
Fact #4 : DNA Fragments Shown To Be Harmless
In the beginning, some studies raised potential safety issues with residual DNA. So, the FDA set an upper limit of just 10 picograms of residual DNA per medicinal dose in 1985.
In 1986, a WHO study group looked into new cell substrates that are being used to produce biological products, and concluded that the risk is negligible when the amount of residual DNA is 100 picograms per dose.
Then 10 years later – the WHO Expert Committee on Biological Standardization (ECBS) increased the limit to 10 nanograms (ng) per purified dose, albeit not for microbial, diploid, or primary cell cultures.
In 1997, the European Medicines Agency (EMA) said that further data of DNA from continuous mammalian cell lines showed that it poses even less risk than previously thought.
Currently, the WHO and US FDA guidelines recommend that residual DNA in vaccines and other biological products should not exceed 10 nanograms (ng) per purified dose, and the DNA fragments should be no greater than 200 bp in length.
Even that limit appears to be out of an abundance of caution, as studies have not shown any actual danger from residual DNA, as they are tiny fragments.
Fact #5 : DNA Fragments Can’t Integrate With Our Genome
The presence of residual DNA fragments does not mean that they will integrate into our genome. For one thing – these are DNA fragments that have been broken down by the DNase enzyme.
Think of them as parts of a factory which were used to build the mRNA vaccine, but dismantled once the vaccine has been manufactured. Sure, the disposal team may have left a couple of bolts and screws lying on the floor, but can they be used to recreate the factory? No.
In addition, these DNA fragments can only enter the cell nucleus if there is an enzyme called integrase, is not present in any COVID-19 vaccine. So they simply cannot enter the cell nucleus, never mind integrate with DNA.
On top of that, the mRNA vaccines are injected into the muscle, whose cells are “post-mitotic”, which means they are no longer able to change.
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