Did Pfizer Add Heart Attack Drug To COVID Vaccine For Kids?

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Did Pfizer secretly add a heart attack drug, tromethamine (Tris), into their newly-approved COVID-19 vaccine for kids?

Take a look at the viral claim, and find out what the FACTS really are!


Claim : Pfizer Added Heart Attack Drug To COVID-19 Vaccine For Kids!

The Alex Jones Show, The Expose UK, Infowars, and Natural News are pushing a new claim – that Pfizer secretly added a heart attack drug to their newly-approved COVID-19 vaccine for kids!

They are suggesting that Pfizer added the drug, Tris, to their COVID-19 vaccine for kids, to reduce the risk of children getting heart attacks as a side effect.

A newly released document shows that drug giant Pfizer added a secret heart attack drug to the children’s version of its Wuhan coronavirus (COVID-19) vaccine.

The Food and Drug Administration (FDA) Advisory Committee that voted 17-0 to approve the jabs for children as young as five was notified that the children’s formulation of the drug contains tromethamine (Tris), a chemical that reduces blood acidity and stabilizes people who have suffered a heart attack.

Did Pfizer Add Heart Attack Drug To COVID Vaccine For Kids?


Truth : Pfizer Did NOT Add Heart Attack Drug To COVID-19 Vaccine For Kids!

This is yet another example of vaccine FAKE NEWS being created and propagated by anti-vaxxers to discourage the vaccination of children.

Pfizer did NOT add any heart attack drug to their newly-approved COVID-19 vaccine for children to reduce or prevent the risk of heart attacks in children.

Everything posted by Alex Jones, Infowars, Natural News or The Expose UK, must be regarded as FAKE NEWS, until proven otherwise.

For those who want more information on why this is false, here are the reasons…

Fact #1 : COVID-19 Causes More Myocarditis / Pericarditis Than Vaccines

The paediatric Pfizer vaccine has, SO FAR, not caused any case of myocarditis or pericarditis, but the sample size is currently too small to know for certain.

The adult dose of the Pfizer COVID-19 vaccine has a rare risk of causing myocarditis or pericarditis in adolescents and young males.

However, what antivaxxers won’t tell you is that COVID-19 itself causes way more cases of myocarditis or pericarditis than the Pfizer vaccine!

For a better perspective of the risk of developing myocarditis, I created this comparison table for you :

Myocarditis Risk Per Million People Difference
COVID-19 Patient 450 +2208%
Pfizer Vaccine
(Adult Dose)
20 +2.6%
Normal Population 19.5 Baseline

As you can see, the risk of developing myocarditis is MUCH higher if your child gets infected with COVID-19, compared with getting a full dose of the Pfizer vaccine.

I have no idea if the myocarditis risk is truly lower with the paediatric dose, but it surely cannot be more than the full dose that is currently being administered to adolescents.

Read more : Pfizer COVID-19 Vaccine For Kids : What You Need To Know!

Did Pfizer Add Heart Attack Drug To COVID Vaccine For Kids?

Fact #2 : Myocarditis / Pericarditis Is NOT Heart Attack

Antivaxxers are trying to conflate the existing myocarditis / pericarditis adverse effect, with a myocardial infarction (heart attack). They are completely different.

Myocarditis / pericarditis is the INFLAMMATION of the heart muscle (myocarditis) or outer lining of the heart (pericarditis), causing chest pain, shortness of breath or feelings of a pounding or fast-beating heart.

It is generally mild, and most will respond well to medicine and rest, and recover completely. They can usually return to normal daily activities once their symptoms improve / resolve.

Myocardial infarction is the IRREVERSIBLE DEATH of the heart muscle due to a PROLONGED LACK of oxygen supply. This is a medical emergency which will result in death if not treated quickly.

Individuals who survive a myocardial infarction will not recover completely, because you cannot restore the dead heart muscle.

Differences pericarditis myocarditis heart attack

Fact #3 : Tris Is NOT A Heart Attack Drug

Tris, which is short for tris(hydroxymethyl)aminomethane or tromethamine / trometamol / THAM in medical use, is an organic compound with MANY uses.

In biochemistry and molecular biology, it is used in buffer solutions (to maintain pH level) especially when there is a need to stabilise nucleic acids.

In medical use, Tris is used to treat metabolic acidosis, as an alternative to sodium bicarbonate. That’s its purpose in cardiac bypass surgery – to correct metabolic acidosis that may occur during or immediately after surgery.

Tris is NOT a drug that treats heart attack. Neither is it capable of preventing heart attacks. So the claim is completely false and nonsensical.

Fact #4 : Tris Is Used In The Moderna COVID-19 Vaccine

The Moderna COVID-19 vaccine has been using Tris or tromethamine as a buffer from the very beginning, to maintain its pH level and stabilise the nucleic acid macromolecules.

If Tris / Trometamol / Tromethamine is truly being added to prevent heart problems as a side effect, then the Moderna vaccine would not have the same problem with myocarditis or pericarditis.

Yet, the Moderna vaccine can similarly cause myocarditis / pericarditis in young males, just like the Pfizer vaccine.

This shows that Tris / Trometamol / Tromethamine has ZERO effect on heart problems.

Pfizer vs Moderna vaccine content

Fact #5 : Tris Is Used To Stabilise Paediatric Pfizer Vaccine

In the new paediatric version of the Pfizer COVID-19 vaccine, Tris replaced phosphate-buffered saline, thereby allowing the vaccine to be stored in a normal refrigerator at 2-8°C for up to 10 weeks.

It isn’t even a secret, as Pfizer openly pointed this out in the VRBPAC Briefing Document for their newly-approved paediatric COVID-19 vaccine.

This modified formulation allows for an improved stability profile and greater ease of use at administration sites.

The modified formulation uses a Tris buffer instead of phosphate-buffered saline (PBS) and excludes sodium chloride and potassium chloride.

The change in buffer is not considered clinically significant.

Pfizer will also use this Tris buffer in updated versions of its COVID-19 vaccine for adults and adolescents.

Fact #6 : Tromethamine Can Be Injected Intramuscularly

Many Google doctors who looked up tromethamine in the use of metabolic acidosis will see that it is usually administered intravenously, and immediately insist that it can only be administered intravenously.

That’s not true. For example, ketorolac tromethamine can either be injected intravenously or intramuscularly. Heck, it even comes in the form of eye drops and oral tablets!

It all depends on what it’s used for, and its formulation.

Ketorolac tromethamine injection

Fact #7 : Only 0.15 mg Of Tris In Each Dose

Each dose of the Pfizer paediatric COVID-19 vaccine contains 0.02 mg tromethamine and 0.13 mg of tromethamine hydrochloride.

For simplicity’s sake – that’s a total of 0.15 mg of Tris / Tromethamine in a single shot. There is 6X more sodium chloride (0.9 mg) than Tris in that shot.

The maximum dose for tromethamine is 500 mg/kg when taken within an hour. A typical 5 year-old child weighs about 18 kg, so we should not exceed 9,000 mg or 9 grams.

In other words – the 0.15 mg of tromethamine in that Pfizer vaccine dose is just 0.00167% of the maximum dose a 5 year-old child can receive.


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Dr. Adrian Wong has been writing about tech and science since 1997, even publishing a book with Prentice Hall called Breaking Through The BIOS Barrier (ISBN 978-0131455368) while in medical school.

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1 Comment

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  11. Stee

    So it’s true then, gotcha.

    By the way, the part where you say that the vaccine causes less myo/pericarditis than covid infection is utterly false.


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